Introduction - Analytical ultracentrifugation service

Analytical ultracentrifugation is a versatile biophysical method for in vitro analysis of proteins, nucleic acids and their complexes. The method was invented by Theodor (Thé) Svedberg in the 1920s. He combined the centrifugation with optical system to allow the detection of sedimenting particles. The unit of sedimentation velocity was named Svedberg [S] after the inventor.

The method can be applied to characterize the following features of proteins and protein complexes:

  • size distribution
  • shape
  • stoichiometry
  • purity
  • homogeneity
  • aggregation
  • homo- and heterotypic binding
  • binding affinities
Legutóbbi frissítés: 2022. 07. 18. 13:03